Endogenfitosterollarsintez qilib bo'lmaydi va faqat ekzogen manbalar bilan to'ldirilishi mumkin. Biroq, sterollarning so'rilish darajasi past, asosan 0,4 foiz 4 foiz. Ushbu maqola sizni fitosterollarning so'rilish jarayoni va so'rilishiga ta'sir qiluvchi omillar bilan tanishtiradi.
Fitosterollarning so'rilishi
Tadqiqotlar shuni ko'rsatdiki, so'rilish jarayonini quyida ko'rsatilgandek 3 bosqichga bo'lish mumkin:
①Phytosterols form mixed micelles with bile acids and free fatty acids in the intestinal lumen;
②The mixed micelles are close to the epithelial cells. The phytosterols are freed from the micelles and absorbed into the cells by the relevant transporters on the cell membrane;
③ The sterol that enters the cell is esterified under the intracellular ACAT enzyme (cholesterol acyltransferase). Then forms chyle with triglyceride and apolipoprotein under the action of MTP (triglyceride transfer protein), which is secreted into the cell. blood circulation system.
Absorbsiyaga ta'sir etuvchi omillar
In general, it decreases with increasing C atoms (campesterol > β-sitosterol >stigmasterol). ning so'rilish darajasifitosterollar in different origins is also different. Such as plants produced in high temperature areas, the proportion of campesterol content is increased, so the absorption rate is also higher. From the perspective of absorption process, esterification is the basis of absorption. The absorption of esterified sterols is 5 times that of non-esterified sterols. Whether the double bond on the carbon atom at the 5th position is saturated also affects the absorption rate, eg campesterol >kampesterol. Ammo beta{0}}glutanol deyarli so‘rilmaydi. So'rilgan o'simlik sterollari jigar, buyrak usti bezlari va jinsiy bezlardagi eng yuqori tarkibga ega bo'lgan tananing turli qismlariga tanlab taqsimlanadi, shuning uchun ular o'sishni rag'batlantiradi va endokrinni tartibga soladi.